Multiple Pathways for Signaling Glutamate Taste in Rodents
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چکیده
منابع مشابه
Multiple pathways for signaling glutamate taste in rodents.
L-glutamate, typically as its Na salt (MSG), elicits a taste termed umami. A characteristic feature of umami taste is the synergistic potentiation of glutamate taste by purine nucleotide (inosine, guanosine) monophosphates. This is manifested as an enhanced electrophysiological response from taste receptor cells, as an increase in nerve firing rate, or as increased preference in behavioral assa...
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L-Glutamate and 5'-ribonucleotides such as guanosine-5'-monophosphate (GMP) and inosine-5'-monophosphate (IMP) elicit a unique taste called 'umami' that is distinct from the tastes of sweet, salty, sour, and bitter. For umami, like sweet and bitter compounds, taste signaling is initiated by binding of tastants to G-protein-coupled receptors (GPCR) in taste bud cells. To date, several GPCRs for ...
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ژورنال
عنوان ژورنال: Chemical Senses
سال: 2005
ISSN: 0379-864X,1464-3553
DOI: 10.1093/chemse/bjh097